Bulma Briefs is one of the world's leading astrophysicists, the world's foremost astronomer, the creator of the Briefs Theory, as well as one of the premiere experts on Planet Vegeta. She found Son Goku after he was banished from Planet Vegeta and fell to Earth while she and her team were in the desert studying astronomical anomalies. She helped him in his mission to return to Planet Vegeta, eventually falling in love with him along the way. They were separated due to the temporary destruction of Planet Vegeta's ships. During Vegeta's assault on Earth, M.O.N. kept her out of harms way by transferring her to a remote observatory where Vegeta could not find her.

She found out of Goku's return through the footage of the Battle of Amestria; this left Bulma disappointed and angry that Goku didn't attempt contacting her. During the Convergence, she became host to a Dragon Ball and helped Goku defeat Majin Buu during the Battle of West City. Once free of the Dragon Ball, Bulma returned to work and Goku had decided to remain on Earth with her. Due to her work studying of the Convergence, Bulma was being considered for the Noble Prize in astrophysics. Following the Father Offensive, Bulma was again separated from Goku, who returned to Planet Vegeta without her knowledge to learn more about the Dragon Balls.